Smartphones are radiotransmitters that emit electromagnetic radiation. The increase in mobile phone usage in the modern era could lead to various health problems. The human auditory system lies close to the source of radiation and is hence at greater risk of absorbing a relatively more significant amount of radiation. The brainstem auditory evoked responses (BERA), being a non-invasive tool allows quantification of the activity and functions of the auditory system. Materials and methods: The systematic review was conducted using the scientific information published from January 2002 to June 2022 using the keywords “smartphone”, “auditory evoked potentials” and “adult population” in different databases to find relevant articles. The review was conducted in adherence to the PRISMA statement. Out of 977 articles screened, 8 articles were selected for review. Results: Out of the 8 studies considered for review, 5 showed that BERA was significantly altered in subjects with prolonged mobile phone usage. In the rest of the studies, though statistically significant results were not produced, latency was prolonged and amplitude was decreased in study groups with prolonged mobile phone usage. Conclusion: Young adults are prone to developing auditory disturbances as they are exposed to the maximum amount of electromagnetic radiation owing to the longer duration of mobile phone usage. Our study concludes that prolonged mobile phone usage has negative consequences on the auditory functions quantified using BERA.