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Solubility Enhancement of Poorly Soluble Nicardipine Utilizing Cyclodextrin Inclusion and Solid Dispersion Technique

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Keywords:
Solubility, bioavailability, dissolution, nicardipine, Solid dispersion, cyclodextrin, kneading technique, solvent evaporation technique

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J. Rajkumar. .1 , Ritesh Rana2 ,N. Bhagyalaxmi3 , Sunitha nagula4 , Puneet Sharma2 , Tanish Sharma2 M.Akiful Haque5 ,Azmath Farhana6
» doi: 10.48047/ecb/2023.12.Si9.298

Abstract

The drug's solubilization affects the drug's absorption or blood levels. A continuous process known as solubility comprises the solute particle migrating freely in solvent media. The degree of dispersion in fluid, accompanied with blood or plasma mobility, determines the biochemical and pharmacological action of a medicine

Article Details

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Volume -12, Special issue-9 (2023 )
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