Sarpagandha is an important Ayurveda drug used for treating many diseases including anxiety, insomnia, hyperactive people as well as antihypertensive effects. Sarpagandha is considered to be a later entry into Indian Materia Medica. Rauvolfia serpentina is the genuine source plant for Sarpagandha and it is a critically endangered species belonging to the family Apocynaceae. The root of Rauvolfia serpentina is the genuine source drug of Sarpagandha. Sarpgandha is mainly indicated in the Ayurvedic texts in Vata rogas, Apasmara and Unmada. It also acts as an antidote to poison