Human life expectancy has increased globally in recent times, yet preventable diseases and mortality continue to be major concerns. Preventive healthcare practices have become more important in a multitude of healthcare fields to alleviate these challenges. Its objectives are to uphold and enhance health, lower risk factors, identify diseases early and minimize repercussions. Health systems can provide primary healthcare, which includes disease prevention, treatment, palliative care, and other services, to meet an individual's health needs. Additionally, this strategy ensures that patients' needs and preferences are supported and that healthcare services are centred around them. If the healthcare system is to be effective, health promotion measures must be incorporated into regular treatment. Health promotion is an essential component of regular family healthcare practice. Health promotion aims to arm people with the knowledge they need to enhance and better manage their health. Family physicians are in the best position to promote and educate about health since they have direct access to the community. Family physicians are increasingly compelled to employ a specialty-centric strategy rather than one that is system-specific or general due to evolving real-world conditions. Various strategies are employed in family practice for disease prevention through health promotion and lifestyle interventions. Moreover, family physicians have a unique opportunity to practice lifestyle medicine and spearhead initiatives aimed at lowering the burden of chronic diseases. Through this review, we aim to elaborately analyze the distinct strategies employed in family practice for the prevention of diseases through health promotion and lifestyle interventions in light of existing literature.