Making use of the definition of adiabatic compressibility, a temperature dependent relation has been deduced to estimate the adiabatic compressibility of binary mixtures at different temperatures from the knowledge of temperature coefficient of density and sound velocity of pure components. The validity of the new relation is examined by comparing the estimated values with those of experimental values for interacting as well as non-interacting binary mixtures at different temperatures. The results obtained were then explained on the basis of molecular interactions present in them.