In various medical systems, numerous herbal remedies have been used to treat and manage various diseases. In various traditional medical practices, the plant Alstonia scholaris has been used to treat human diseases and ailments. It is said to contain phenolic acids, flavonoids, and various alkaloids. It has been shown to have antimicrobial, antiamoebic, antiplasmodial, hepatoprotective, immunomodulatory, anticancer, antiasthmatic, antioxidant, analgesic, anti-inflammatory, anti-ulcer, anti-fertility, and wound healing properties. Additionally, there are reports indicating that this plant is traditionally used for its cardiotonic, anti-diabetic, and anti-arthritic properties. There are no reports of pharmacological activities for many Alstonia scholaris isolated constituents, which would support their subsequent pharmacological studies.