The ficus Religiosa also known as peepal and it is a traditional plant which are located near the temples in india for spirituality. This plant used in treatments and cure of diseases. Its consists different kinds of chemicals constituents like alkaloid tannins, phenols, saponins, sugars ,essential oils methionine, terpenoids,flavonoids, glycosides, proteins, separated amino acids ,volatile oil ,etc and it is also have different types of pharamacological properties antiParkinson's, anticonvulsant, anti-amnesic, anticholinergic, antidiabetic , analgesic, cytotoxic, anti-ulcer, wound healing, antioxidant, anti- asthmatic, reproductive antimicrobial, antiparasitic,which are use in different kinds of diseases. Different part of ficus religiosa used in different diseases.Here we are studies the Antiulcer property of ficus religiosa with ethanolic extract of leaf (200- 500mg/kg) on inducing stress ulcer in animal model and Ranitidine is standard drug .In results the ethanolic extract of leaf of ficus Religiosa is prevent ulcer and protect the gastric mucosa, gastric secration and these are analysed in dose dependent manner .