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ISSN 2063-5346
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Study of Firmicutes and Bifidobacterium phyla in Patients with Type 2 Diabetes mellitus

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1Mohamed Mohsen Motawea, 2Maysaa El Sayed Zaki, 3Ahmed Gomaa Ahmed El Sayed, 2Emad Ibrahim Mohamed El Masry
» doi: 10.48047/ecb/2023.12.10.857

Abstract

Background: Gastrointestinal microbiota may play a vital role in pathogenesis of type 2 diabetes mellitus (DM). Firmicutes phyla and Bifidobacterium phyla represents the major components of the microbiota in gastrointestinal tract. Aim: The aim of this study was to investigate the ratio of phyla Firmicutes and Bifidobacterium in patients with type 2 DM compared to apparently healthy control subjects by real time polymerase chain reaction (PCR). Method: The study was a retrograde case control study that included 100 patients with type 2 DM and 100 control subjects. Firmicutes phyla and Bifidobacterium phyla were determined in the stool samples by real-time PCR.

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