There is no single, accepted definition of what quality of life is. It is usually believed to be a multidimensional construct that assesses various facets or "domains" of life, such as functional, psychological, social, and physical well-being. However, the idea is inherently arbitrary because it depends on the patient's "appraisal" of how well they are now performing in relation to their ideal level of functioning. The Functional assessment of Cancer Therapy (FACT-G) scale is regarded to be the most acceptable scale to check the (QOL) of the cancer patients. The main aim of the study is to check the Quality of Life in oropharyngeal cancer patients. The objectives of the study are to evaluate the scores and check if palliative care can improvise the patients Quality of Life. Methodology: This was a observational type of study in simple random sampling technique was used . This study was conducted in Krishna Vishwa Vidyapeeth in the oncology department , palliative care unit for a duration of 6 months . A total of 50 oropharyngeal patients were included in the study who filled up the questionnaire .The questionnaire comprised of 4 different section with a total number of 27 questions. The questionnaire was given to the patient individually and filled and then the responses were analyzed using the Instat software. Results : Responses were given by 50 respondents where the results showed that 45% of the patients were content with the Quality of Life they have after being detected and some being operated for oropharyngeal cancers with the benefits of palliative care treatment. Conclusion: The study concludes that only moderate level of patients are aware and benefited through the palliative care while there is much need to spread awareness and knowledge about the benefits that palliative care can have on patients Quality of Life