Cardiomyopathy is a disease of myocardium that results in poor myocardial performance and is not caused by disease or malfunction in other cardiac components. Present study was aimed to periodical screening of ECG and ECHO changes in order to improve the longevity of dilated cardiomyopathy patients. Material and Methods: Present study was cross sectional study, conducted in patients of age > 18 years, either gender, echocardiography findings suggestive of dilated cardiomyopathy (LV ejection fraction <45%, LV end-diastolic dimension >3 cm/body surface area, LV diastolic dysfunction & Global hypokinesia). Results: Among 87 patients, males and females were 56.3 % and 43.7 % respectively. Breathlessness was the commonest symptom noticed (82.8 %) followed by palpitation (62.1 %), cough (62.1 %), PND (55.2 %) & orthopnea (48.3%). Among signs observed, common signs were basal crepitations (87.4 %), raised JVP (73.6 %), pedal edema (67.8 %), hepatomegaly (49.4 %) & LV S3 (49.4 %), Most common type of DCM was ischemic DCM (51.7 %), followed by idiopathic cardiomyopathy (16.1 %), diabetic cardiomyopathy (14.9 %) & alcohol cardiomyopathy (4.6 %). Common ECG findings were sinus tachycardia (51.7%), VPC (26.4%), atrial fibrillation (13.8%), sinus bradycardia (8%) & RBBB (4.6%). The mean LV ejection fraction in our study group was 31.6 ± 7.7 %. The mean LV end diastolic diameter was 6.0 ± 0.8 cm. The mean LV end systolic diameter was 4.9 ± 0.6 cm. Other parameters were MR (73.33 %), TR (10 %), Pericardial Effusion (6.6 %) & LV clot (3.3 %). Conclusion: Among dilated cardiomyopathy patients electrocardiographic profile consisted of ventricular ectopics, sinus tachycardia, left bundle branch block, Atrial fibrillation, right bundle branch block, atrial ectopics, ventricular tachycardia and complete heart block. Echocardiographic profile included reduced ejection fraction and global hypokinesia in all the patients.