The properties of materials are often enhanced for applications in areasautomotive, marine, aerospace, petrochemical and oil industrials where components are regularly exposed to atmospheric contaminant and corrosives, which eventually leads to loss in mechanical properties such as wear resistance, hardness and nanoindentation resistance. In view of these challenges, titanium grade 5 was coated with Inconel 625 using themagnetron sputtered coating technique, varying the process parameters such as temperature, power and deposition time.The chamber utilized for the magnetron sputtering was appropriately vacuumed at a base pressure of 1.13 x 10-5 mbar. The wear characteristics of the Inconel coated titanium samples using tribometer of 8.1.8 version in accord with ASTM G99 criterion, at a normal load of 10 N. A nanoindenter was employed to study the micro-hardness of the samples at 400.0 Hz in accordance with ASTM A-370. The indentation work done during plastic deformation (Wplast.) and elastic deformation (Welast.) was also examined.Relative to the other test samples, the ICT C sample (sample coated at the temperature of 200oC, time of 90 minutes and power of 200 W) possessed the least wear rate of 0.001064 mm3/N/m. Similarly, the ICT C sample exhibited the highest micro hardness, as indicated by the Vickers hardness value which is 544.57 μN/mm2. More so, the ICT C sample exhibited the lowest Welast. and Wplast. values. These results indicated that the ICT C sample exhibited the lowest material loss, superior plasticity and elasticity, higherstrengthand great resistance to nanoindentation.