The concept to eliminate or reduce the generation and/or use of toxic and hazardous reagents by the design of chemical products and processes is known as green chemistry. In 1998, 12 Principles of green chemistry were published to provide guidelines for the further development of industries. Green chemistry is the design of chemical products and processes that reduce or eliminate the use or generation of hazardous substances. Since the last decade, this concept is given special focus like conferences with the specialized theme of green chemistry, journals publishing special issues, books, etc. So many industrial processes are explored to demonstrate the application of the appropriate green chemistry principle. Each principle is connected with an appropriate industrial case to make a better understanding application. Different industrial examples are searched and compiled which represent a real-time industrial application of each principle of green chemistry. The reader will have a ready example of each principle to understand its industrial applications.