Introduction: Lichen amyloidosis is a chronic skin condition characterized by the appearance of lichenoid papules accompanied by itching. Treatment of lichen amyloidosis can be topical such as; corticosteroids and tacrolimus, as well as systemic such as; administration of cyclosporine or retinoids, dermabrasion, and chemical peels. Case: A 68-year-old man of Batak ethnicity came to the Dermatology and Venereology Polyclinic at the Universitas Sumatera Utara Hospital complaining of hard brown nodules accompanied by itching on the right lower leg since ± 3 years ago. Physical examination was within normal limits; dermatological examination found brownish, miliary-lenticular, multiple hyperkeratotic papules in the right cruris region—complete blood laboratory examination within normal limits. Histopathological examination supports the diagnosis of lichen amyloidosis. Therapy was given in the form of 0.05% clobetasol propionate and 10% salicylic acid applied in the morning and evening, cetirizine tablets 10 mg once a day for four weeks. Then proceed with chemical peeling with 15% trichloroacetic acid (TCA), which is done every two weeks. Good clinical improvement was seen after four sessions of chemical peels. Discussion: Topical corticosteroids are effective and safe for various dermatotic conditions, but their use is not recommended for the long term because they can cause unwanted side effects. Application of 15% to 30% TCA peels in lichen amyloidosis patients can significantly reduce itching and improve clinical outcomes. Conclusion: Combining topical therapy with chemical peels for lichen amyloidosis provides significant clinical improvement.