Volume - 13 | Issue-1
Volume - 13 | Issue-1
Volume - 13 | Issue-1
Volume - 13 | Issue-1
Volume - 13 | Issue-1
This study focuses on synthesis and biological evaluation of a diverse library of more than fifty novel imidazole-based compounds. The objective was to investigate their potential as antibacterial and antifungal agents. Heterocyclic and fused heterocyclic compounds have been extensively explored in drug development due to their biological and synthetic utility. Imidazole compounds, in particular, hold great importance in medicinal chemistry. The research comprises three main parts. Firstly, an extensive literature survey was conducted to identify biologically active imidazole compounds associated with antibacterial and antifungal activities. Based on this knowledge, the second part involved the rational design of target compounds using well-known drugs such as clemizole, etonitazone, envioroximal, astemizole, omeprazole, pentoparazole, and thiabendazole, which possess imidazole/benzimidazole heterocyclic or imidazole nucleus as the pharmacophoric group