Synthesis of 2-[(4-methyl-2-oxo-2H-chromen-7-yl) oxy-(aryl)] acetamide was the goal of this project activity..CDCl3 was the common solvent for all the compounds. A significant affinity for 5-HT receptors, one of the key properties of atypical antipsychotics, was validated by the literature study. evaluation of their melting temperatures, Rf values (derived from TLC), Spectral of the (1HNMR) or infrared (IR) light were used for the physicochemical characterisation.