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ISSN 2063-5346
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SYNTHESIS AND EVALUATION OF THE SELECTIVITY AND POTENCY OF TRIPHENYL IMIDAZOLES AS POTENTIAL ANTI TUBERCULAR AGENTS

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Saroj Kumar Sahoo, Umarani Wunnava, Murali Krishna Kumar Muthyala
» doi: 10.48047/ecb/2023.12.7.101

Abstract

Tuberculosis is an infectious disease with a high rate of mortality; it requires a prolonged period of treatment with many multi drug resistant strains of the bacterium highly prevalent. This problem needs all hands on deck to ensure a varied arsenal of molecules to ensure proper treatment of this scrouge preying on the world. This paper explores the susceptibility of Mycobaterium tuberculosis H37RV strain to triphenyl imidazoles synthesized from benzils. Two of the synthesized compounds exhibited anti tubercular activity comparable to that of the standard drug.

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