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ISSN 2063-5346
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SYNTHESIS AND PHARMACOLOGICAL EVALUATION OF NEW QUINAZOLINONE DERIVATIVES AS ANTI DIABETIC AGENTS

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Ritesh Patel*1 , Pritesh Paliwal2 , Praveen Sharma3 , Rohit Sahu4 , Gaurav Agrawal5 , Dheeraj Jain6 and Santosh Ghule
» doi: 10.48047/ecb/2022.11.12.148

Abstract

In this study, a library of new 4-[6-chloro-2-arylaminoethyl-4-oxoquinazolin3(4H)-yl] benzoic acid (Q1-Q16) were synthesized and evaluated for their in vivo antidiabetic activity. All the compounds were prepared in a multistep process involving the initial preparation of 5-chloro-N-acetyl anthranilic acid which was converted to 4-[6-chloro2-methyl-4-oxoquinazolin-3(4H)-yl] benzoic acid

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