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ISSN 2063-5346
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Synthesis, Characterization and Evaluation of Anticancer Activity of (5-(Benzo[d][1,3]Dioxol-5-yl)-3-(2-Methoxyphenyl)-4,5-Dihydro-1H-Pyrazol-1-yl)(Furan-2-yl)Methanone

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Dr. Vinodhini.V1*, Rozario Cyril2, Dr. Deepa.E3, Dr. Malathi.S4, Kalaichelvi. A5
» doi: 10.31838/ecb/2023.12.4.035

Abstract

Compound (5-(benzo[d][1,3]dioxol-5-yl)-3-(2-methoxyphenyl)-4,5-dihydro-1H-pyrazol-1-yl)(furan-2-yl)methanone was prepared using chalcones. The compound produced was subjected to different spectroscopical analysis like IR, 1H-NMR, 13C-NMR and mass spectra for characterization. The compound was subjected to cytotoxicity activity testing by MTT assay using MCF-7 cell line. The compound is also subjected to cell cycle analysis by Flow cytometry. The compound has shown cytotoxicity effect and also has the ability to cause arrest of cells in cell cycle at the G2/M phase of the MCF-7.

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