This study is concerned with the synthesis and characterization of derivatives of 1H-1,2-dithiol-1-thiones and thioamides having the hydroquinoline moiety. 5-Alkyl-8-(carbonothioyl)-4,5-dihydro-4,4-dimethyl-1H-[1,2]dithiolo[3,4-c]quinoline-1-thiones were synthesized by reacting of N-alkyl-2,2,4-trimethyl-1,2-dihydroquinoline-6-carbaldehydes, cyclic secondary amines and excess elemental sulfur (7.33 equivalents) in refluxing DMF. A series of thioamides derivatives containing hydroquinoline fragment were obtained in 56-84% yields by the three-component reaction of N-alkylhydroquinoline-6-carbaldehydes, cyclic secondary amines and 1.33 equivalent of elemental sulfur by refluxing in DMF