The synthesis of new series of compounds was undertaken with the aim of exploiting immense potential of carboxylic acid derivatives and be able to come up with the most active biological activity profile. The titled compounds (1-8) were synthesized by stirring naphthoxy acetic acid hydrazide with corresponding aromatic aldehydes. The hydrazide was synthesized from the acid via its esterification followed by its nucleophilic substitution reaction i.e. hydrazinolysis with hydrazine hydrate. All the synthesized compounds were characterized on the basis of IR and 1H-NMR spectroscopy techniques. All the final compounds were evaluated for their antimicrobial property using cup plate method. The antimicrobial result of newly synthesized compounds revealed that all the compounds showed moderate to good antimicrobial activity against the tested strains.