The characteristics of the cancer that offer chances for medication delivery systems to target cancer this term are highlighted in this article. The most promising approach that can bypass has received a lot of attention despite the fact that chemotherapy-based targeted medication delivery has been the subject of much research. The extensive introduction of targeted delivery techniques based on different nanocarriers to incorporate small molecule chemotherapies in the treatment of cancer was also addressed in this review. The difficulties in using a tailored medication delivery system to treat cancer are also mentioned in this article.