In India, though Oral Cancer ranks among the top 3 cancers according to their prevalence rate, still huge dearth in the availability of literature assessing &evaluating the quality of life of tobacco related oral cancers. QOL is largely affected by lot of overlapping facts and domains. Though enormous health care research is happening through out entire globe to improve the survival and to improve the quality of life in all the cancers of human body. Human being s individual perception for quality of life is among the significant and most important parameter to enhance the overall well being of patients of cancer.