Aim of work: To detect the overall diagnostic performance of 68Ga-DOTATATE PET/CT in the assessment of recently diagnosed NETs and follow-up the patients after different treatment regimens. Patients and methods: A prospective analysis of 98 NETs patients, the study includes 50 females and 48 males with ages between 25 to 68 with mean age of 49. The patients were referred either to confirm the diagnosis of suspected NETs (clinically doubtful patients or with laboratory and image-based suspicion), or to initial stage confirmed cases, or for posttherapy assessment. All patients performed 68Ga-DOTATATE PET/CT scans. Any localized or patchy inhomogeneous uptake greater than the background and located outside the normal anatomic structure was considered as DOTATATE avid lesions. Available follow-up DOTATE PET/CT scans for 19 patients were interpreted visually and semiquantitative according to the PERCIST criteria.