Background: The purpose of the present study was to investigate the effect of using the intraoral scanning from the point of view of dentists and dental lab technicians in Najran region, Saudi Arabia. Materials and methods: This study is a cross-sectional study, conducted using a questionnaire that were was randomly distributed online to Saudi dentists and dental-lab technicians in Najran region. The questionnaire consisted from three sections of questions: 1) questions about personal information, 2) questions about the features of using the intraoral scan, 3) questions about the extent of relying on intraoral scanning in dental clinics and labs in Najran region. About 178 of dentists and dental lab technicians completed the questionnaire. The statistical analysis program (SPSS v.26) has been used in the study in data entry and analysis, with using the necessary statistical methods to achieve the objectives of the study. Results: 68.0% of participants were males and 32.0% were females, the majority of participants aged between 30-40 years old, 35.4% of participants had working years >16 years. The total degree of the efficiency of using the intraoral scan from the point of view of dentists and dental lab technicians was high (M = 4.19 out of 5, RII = 83.9%, SD = 0.86). The prevalence of intraoral scanners in the dental clinics and labs was 86% in Najran region.49.4% knew the effects of different lights on intraoral scanning. 79.8% knew the unit of measure light intensity. 64% knew the indications of intraoral scanning. Conclusion: Dentists and dental-lab technicians in Najran region thought that the using of intraoral scanning in dentistry is effective.