Objectives: This review explored the relationship between knowledge among children and adolescents and their dietary behavior. Content: Potentially eligible original research articles were identified through a systematic search in PubMed, SCOPUS, Web of Science and WHO Virtual Health Library from 2000 to 2022. From the initial search, a total of 8,258 research articles were obtained. Duplicate studies were identified and removed. Observational studies on children and adolescents (5–16 years) of any gender, ethnicity and country were included in which the outcome measured was either a scoring of/ association between nutrition knowledge and practices. After screening using the inclusion criteria, 10 studies were selected for this paper. The quality of studies was assessed using the revised Cochrane risk of bias tool by two independent reviewers.