Background: Hospitals are investing in health information technology (HIT) to improve the nation's healthcare system. HIT uses computer hardware and software to organize health-related data, promote dialogue, and assist in decision-making. Saudi Arabia has made significant progress in HIT, enhancing patient care, safety, and overall healthcare quality. However, challenges such as low computer literacy and IT staff support remain. A survey in Jordan and Palestine found that most hospital departments use computer systems, but half need specialized training in health informatics (HI). Objective: The general objective of this study is to assess the impact of health informatics on healthcare quality and patient outcomes in Saudi Arabia in 2022. Conclusion: This research project evaluates the impact of health informatics on healthcare quality and patient outcomes in Saudi Arabia in 2022. Health informatics improves treatment quality, reduces care-processing time, and increases patient satisfaction. It also aids clinicians in acquiring diagnostic data, providing drugs, reducing medical errors, and managing physician/nurse teams. However, challenges like low computer literacy persist. Health informatics positively impacts healthcare workforce development, training, research, and innovation, facilitating new treatments and improving patient outcomes.