Interdisciplinary team-based care involving general practitioners (GPs), pharmacists, and nurses has gained recognition as a promising approach to improving patient outcomes in chronic disease management. This review article explores the impact of such collaborative care models on patient quality of life. By integrating the expertise of multiple healthcare professionals, interdisciplinary teams can provide comprehensive and coordinated care that addresses the complex needs of patients with chronic conditions. The synergistic interactions among team members contribute to enhanced patient outcomes, including improved quality of life, medication adherence, and disease control. This review synthesizes current evidence on the effectiveness of interdisciplinary team-based care in chronic disease management and highlights key factors that influence its success. Furthermore, it discusses the challenges and opportunities associated with implementing and sustaining interdisciplinary care models in clinical practice. Overall, the findings suggest that interdisciplinary team-based care involving GPs, pharmacists, and nurses holds great promise for optimizing patient quality of life and health outcomes in chronic disease management.