In modern healthcare settings, laboratory tests play a crucial role in diagnosing and monitoring various medical conditions. Effective interpretation and utilization of these tests are essential for providing high-quality patient care. Nurse-led education programs have emerged as a valuable strategy to enhance nurses' knowledge and skills in interpreting and utilizing laboratory test results. This review article aims to explore the impact of nurse-led education on laboratory test interpretation and utilization. A comprehensive literature review was conducted to identify relevant studies that investigated the effectiveness of nurse-led education programs in this context. The findings suggest that nurse-led education can significantly improve nurses' ability to interpret laboratory test results accurately and use them to inform clinical decision-making. By enhancing nurses' understanding of the significance of different laboratory tests and their implications for patient care, nurse-led education programs have the potential to improve patient outcomes and enhance the quality of healthcare delivery. This review highlights the importance of investing in continuous education and training for nurses to optimize the utilization of laboratory tests in clinical practice.