Introduction: Complete blood count (CBC) is a blood test which is commonly requested by clinicians in a haematology laboratory. It is used to measure various components of blood, out of which the most frequently asked isolated parameter is Platelet count. The platelet count is evaluated by the automated analysers in the laboratory, which shows histograms and warning flags about the platelet’s interpretation. But the validity of the automated analyser results are sometimes not reliable. Pseudo-thrombocytopenia (PTCP) is an in-vitro phenomenon of false low platelet count, given by automated analyser. PTCP if not detected leads to unnecessary diagnostic tests and mismanagement occurs. Hence study is done to stress the role of visual inspection of all the blood smears with thrombocytopenia before alerting the clinician about it. Objectives: To evaluate the percentage of pseudothrombocytopenia cases in the total thrombocytopenia cases and to evaluate the role of peripheral smear examination as confirmatory test for platelet count in cases of thrombocytopenia. Methodology: Platelet count of EDTA samples determined by the automated haematology analyser Sysmex XN – 550 showing values less than one lakh were collected. Leishman stained peripheral smear were visually inspected for any presence of platelet clumps, giant platelets and manual count done to identify cases of pseudo-thrombocytopenia and results documented. Results: The incidence