Background: To investigate prescribing of antibiotics practices for various endodontic diagnoses and clinical scenarious by general practitioners, post-graduate students and endodontists in India. Materials & methods: A link for an online questionnaires consisting of two parts; the first part includes demographic information like name, age, designation of endodontontic practice; the second part contains the questions related to decision about antibiotic while treating endodontic infections was invited to dentists through google form. After collection of the responses, a chisquare test was performed using SPSS v21.0 software.