The advancement of microfluidic methods, when combined with drug screening and biomolecular diagnostics, provides a pathway towards customized medical treatment that is supported by empirical data. For optimal results, it is ideal to do personal diagnostics quickly and often, and a microfluidic interface may provide the proper approach. Enabling genetic analysis or biomarker identification at the point-of-care would empower clinicians to make more informed decisions about therapy. Proposals have been made for microfluidic devices that may be used to analyze biomolecules at various levels, ranging from genes to whole tissue biopsies. The majority of the work shown here is in its first phase of development, but it will explore many design factors and the multitude of possible uses of integrated microfluidic technology.