Nutrition and health are deeply correlated just as a genotype to an organism. The study of how food affects genes of an individual along with how they affect the manner his body responds to food is essential in present day scenario. Nutrigenomics provides us important knowledge to learn more about how both genes and diet work together and affect a person’s health and risk of developing many ailments. It is an emerging biological and medical science that investigates and employs tools to access the numerous responses reported through a planned type of diet and applied for an individual and population. Nutrigenomics includes nutrigenetics , epigenomics , transcriptomics along with study of nutrients and bioactive compounds of food through proteomics and metabolomics e.g. there are certain epigenetic changes that could be removed or added in the form of response to various changes in environment or behavior for examples after quitting smoking, smokers were seen to have increased DNA methylation even at gene level. Nutrigenetics is the science that deals with the effects of variation of genetics of an individual on response to certain diets, that may lead to personalized dietary formulations and recommendations in the long run, Transcriptomics on the other handmay be utilized to provide detailed information about mechanisms of a particular diet or nutrient. It could also aid in knowing the way any gene, metabolite or protein may result in changes in patterns of diseases in its various phases or the benefits of various nutrients in preventing diseases or resulting in good health.