Background- Osteoarthritis is a degenerative disorder of joints that involves cartilage destruction, subchondral bone thickening, and new bone formation at the joint surface. The centre of foot pressure is the point of origin of ground reaction force. (GRF) which is probably the most important force during locomotor activities. Pressure plate analysis is a test done to measure the forces going through one’s feet as they go about their activities like walking, running, lifting loads, and so on. This is used for analysis of gait parameters in patients with OA. Objectives- To quantify, compare, and correlate the foot COP deviation, pain, clinical scores, disability, and radiographic analysis in normal and grade II Osteoarthritis patients. Methodology- A total of 45 patients including both male and female were selected out of which 30 were grade II knee OA and 15 were normal subjects (Grade 0). Each patient was assessed for disability using WOMAC, pain using NPRS, walking ability using clinical scores, and gait parameters using a pressure plate. Results- Data was analyzed using SPSS software. There was a significant relationship between stance time, clinical scores, WOMAC, NPRS and there was a significant correlation between the gait parameters obtained by our method and the clinical evaluation results. Conclusion- The study concluded that there was a deviation in center of pressure and gait parameters among subjects with grade 2 OA knee.