Pulmonary tuberculosis (TB) is one of the infectious diseases that has become a globalproblem, for developing countries such as Indonesia. TB problems are exacerbated by comorbidities, one of which is Diabetes Mellitus (DM). The purpose of the study was to applythe transhare model (Creation knowledge, Transfer knowledge and knowledge sharing) to control the transmission of Pulmonary Tuberculosis in patients with Diabetus mellitus. Experimental research design with crossectional approach. In accordance with the inclusion and exclusion criteria, a large sample of 17 respondents with DM-TB for the transharemodel intervention group and 17 respondents with DM-TB for the control group were taken based on total sampling. The dependent variable is the transhare model including: create knowledge, share knowledge and transfer knowledge, while TB transmission control includes respondent characteristics, control compliance, medication adherence, and environmental conditions. Statistical analysis of Transhare Model using Ordered probit regression with the help of Stata 16 The results of the statistical ordered probit regression model showed significant valuesin creation knowledge: room temperature (2.061*), control compliance (-2.081***); knowledge transfer: duration of treatment (-1,585*); knowledge sharing: Education (1,022*), room temperature (-4,330***), humidity (3,282**), control compliance (1.794**) . The conclusion of the study states that home conditions with temperature and humidity,control compliance and medication adherence encourage someone to do knowledge management in overcoming the transmission of pulmonary tuberculosis.