This research paper explores the utilization of infusion molasses and plastic waste as partial replacements for bitumen in asphalt mixtures, presenting a sustainable approach for road construction. Laboratory testing is conducted to assess the performance of different asphalt mixtures incorporating varying percentages of infusion molasses and plastic waste. Results demonstrate that these alternative materials can effectively enhance the engineering properties of asphalt mixtures, improving workability, moisture resistance, stiffness, and rutting resistance. The findings highlight the potential of this approach to reduce environmental pollution, conserve resources, and foster a circular economy in the construction industry, emphasizing the need for further optimization and implementation on a larger scale.