The Fibre post most frequently fails at adhesive interface between resin cement and dentin. The objective of this study is to evaluate the effect of antioxidant sodium ascorbate and a new homeopathic agent on the pushout bond strength of fibre post to root dentin treated with and without LASER. Extracted hundred (100) single rooted teeth were collected, decoronated and working length was determined. Instrumentation and irrigation were performed using irrigants with 2 ml NaOCl and 0.5 ml of 17% EDTA for 3 min. After obturation post spaces were prepared. The specimens were divided into 5 groups (n=20) and post spaces were irrigated; G1= normal saline 5ml for 2 min, G2=10% Sodium ascorbate 5 ml for 2 min, G3= Hypericum perforatum 5ml for 2 min, G4= Laser with 10% Sodium ascorbate 5 ml for 2 min, G5= Laser with Hypericum perforatum 5 ml for 2 min. The post spaces were dried with absorbent paper points. Bonding agent was applied in the post space and posts were luted. The teeth underwent thermocycling for a week and from each sample 2mm thick horizontal slices were obtained from cervical third of root. The pushout bond strength test was carried out using Universal testing machine. The data was statistically analysed using Student’s Unpaired “t” and ANOVA test.