With the advancements in weapon technology, ammunition has become more precise and lethal. The civil structures required for storage of ammunition and for carrying out special operations have become vulnerable to the blast and shock loads of modern weapon systems. There is a need for innovative and indigenous design of Blast Valve which can fulfil the requirements of ventilation of such structures. The design demands that this device shall be automatic, inexpensive, reliable) and Computational Fluid Dynamics (CFD) are employed for modelling and simulation of blast valve. The shock-structure interaction analysis of different configurations of the blast valve are performed using ANSYS AUTODYN in order to optimise the design. One of the most important components of the blast valve is circular plate exposed to blast loadings. To understand the effect of blast wave on circular plate and hemispherical shells, the experiments are performed using a shock tube test facility. Plates and shells of different thickness and curvature are subjected to varying blast loads, and strains at different locations are measured in order to optimise the same. The whole exercise in the present research work is carried out to address leakage problem in existing blast valves in order to achieve a design of blast valve with minimum or no leakage.