INTRODUCTION: Awkward posture, repetitive work, manual handling of loads, overuse and work sites ill adapted may cause a broad range of musculoskeletal disorders. “A Pre-experimental study to assess the effectiveness of structured teaching program on Ergonomics among Multi-Purpose Workers in selected hospitals of Pune City”. Objectives of study 1) To assess the knowledge regarding Ergonomics among Multi-Purpose Workers before giving structured teaching program. 2) To assess the knowledge regarding Ergonomics among Multi-Purpose Workers after giving structured teaching program. 3) To assess the effectiveness of structured teaching program on Ergonomics among Multi-Purpose Workers. 4) To associate the findings to selected demographic with the level of knowledge of Ergonomics.