The structural behavior of reinforced concrete flat plate is different as compared with beam supported slabs as flat plate is directly supported on columns. Sometimes the modification of the structure demands for the structural changes such as the removal of the portion of the slab, i.e. the opening in the existing slab or in the newly constructed work. The opening is required for the electrical and plumbing services, also required for the installation of lifts, escalators. The openings in slabs reduce the slabs load carrying capacity; shear capacity, stiffness, and ability to control deflection. The various strengthening techniques were introduced by researchers to restore the capacity of these mentioned parameters. The present study aims to review the effect of opening and various strengthening measures to restore the structural behavior of reinforced concrete slabs.