Objective: The main focus of the study was to extract, isolate and characterize the phytochemical compounds for its antidiabetic activity from various parts of ficus glomerata. Methods: Extraction of the compounds were done by the method of soxhlation. Extract were subjected to isolation of compounds which were evaluated for its antidiabetic activity through invivo evaluation on male wistar rat by determining the glucose lowering effect after administration of isolated compound. Result: The result obtained from the invivo evaluation of glucose lowering effect showed potential owering of blood glucose level to substantial level by administration of isolated compound with a dose of 20mg/kg as compared to standard glibenclamide drug. Conclusion: the research found to conclude that the isolated compound have a substantial glucose lowering effect on the male wistar rat. The antidiabetic effect can be further enhanced by increasing the dose and improving bioavailability through various dosage form.