Background: Emergency departments (ED) play a crucial role in providing urgent healthcare services to millions of critically ill patients annually in the United States. However, challenges such as increased medical error rates, wait times, and overcrowding have highlighted the need for innovative solutions. Telemedicine, defined as remote healthcare services using technology, has emerged as a promising approach to enhance emergency care delivery. By enabling remote consultations, telemedicine offers convenience, accessibility, and potential cost savings in emergency settings. Objective: This study aims to assess the effectiveness, quality, cost-effectiveness, barriers, and satisfaction levels associated with implementing telemedicine in emergency care. Specific objectives include evaluating access improvement, care quality, cost-effectiveness, identifying challenges, and exploring satisfaction levels among patients and healthcare providers. Conclusion: Telemedicine applications in emergency care have shown promising results in various aspects, including reducing unnecessary transfers, improving treatment times, enhancing access to care, and increasing patient satisfaction. While there are barriers such as limitations in physical examinations, technical issues, and privacy concerns, adherence to regulations and standards can mitigate these challenges. The use of telemedicine in emergency situations has the potential to enhance the quality of care, improve patient outcomes, and streamline healthcare delivery. Continued research and optimization of telemedicine practices are essential to maximize its benefits and address existing barriers in emergency care settings.