Ocular administration of drug is primarily associated with the need to treat ophthalmic diseases.The vesicle is made up of a bilayer of non-ionic surfactants, thus the name niosomes.Niosomes are extremely small and microscopic (on a nanometric scale). The niosomes are classified as a function of the number of bilayers (e.g. MLV, SUV) or as a function of size. (E.g. LUV, SUV) or as a function of the method of preparation (e.g. REV, DRV). Tthe characterization of noisome was experimented by different methods and the results was evaluated. Niosomes are vesicles composed of non-ionic surfactants, which are biodegradable, relatively nontoxic, more stable and inexpensive, an alternative to liposomes