This study aims to investigate the effect of Lannea coromandelica bark extract on lipid peroxidation activity and the degree of lung damage in male Wistar rats given MSG. This study used 25 rats divided into five treatment groups: healthy control group with standard feed, negative control with monosodium glutamate, treatment group 1 (Lannea coromandelica extract 250 mg/KgBW + MSG administration), treatment group 2 (Lannea coromandelica extract 500 mg/KgBW + MSG administration) and treatment group 3 (Lannea coromandelica extract 500 mg/KgBW + MSG administration). The administration of Lannea coromandelica extract and MSG was carried out for 28 days. Subsequently, lung organs of rats were surgically removed, which were then analysed for malondialdehyde (MDA) levels as a biomarker of lipid peroxidation, and the degree of lung damage through histopathological examination. This study showed that the group given Lannea coromandelica extract, especially at a low dose (250 mg/kgBB had significantly lower MDA levels than the group given only MSG (p = 0.045). However, the administration of Lannea coromandelica extract showed no significant effect (p>0.05) on the degree of damage to the rat lungs when compared to the negative group. The use of Lannea coromandelica bark extract showed potential in protecting lung damage caused by excessive MSG administration.