Nurse empowerment, defined as the ability of nurses to make autonomous decisions and take control of their work environment, has been increasingly recognized as a key factor in enhancing patient safety outcomes. The literature suggests that empowered nurses are more likely to engage in proactive safety behaviors, such as effective communication, error reporting, and advocating for patients' needs. Moreover, empowered nurses tend to exhibit higher levels of job satisfaction and commitment, which are known to positively impact patient care quality and safety. This review synthesizes existing research on the relationship between nurse empowerment and patient safety, highlighting the mechanisms through which empowered nurses contribute to a safer healthcare environment. Implications for nursing practice, education, and policy are discussed, emphasizing the importance of fostering a culture of empowerment to improve patient safety outcomes.