Nursing advocacy plays a crucial role in promoting patient rights and safety in the emergency room (ER) setting. This review article aims to explore the significance of nursing advocacy in ensuring that patients receive high-quality care and their rights are upheld in the fast-paced and often stressful environment of the ER. The review will examine the various ways in which nurses act as advocates for patients, including communicating patient concerns to the healthcare team, ensuring informed consent, and safeguarding patient confidentiality. Additionally, the article will discuss the challenges that nurses face in advocating for patients in the ER, such as time constraints, resource limitations, and hierarchical structures within healthcare organizations. By highlighting the importance of nursing advocacy in the ER, this review seeks to underscore the essential role that nurses play in promoting patient-centered care and safeguarding the well-being of individuals seeking emergency medical treatment.