This review article examines the crucial role of nursing staff in promoting oral health within the general population. Oral health is a significant aspect of overall well-being, with implications for systemic health and quality of life. Nursing staff play a vital role in oral health promotion through education, assessment, and preventive interventions. This review explores the various strategies and interventions employed by nursing staff to enhance oral health outcomes in diverse populations. The impact of nursing-led oral health programs, including screenings, education initiatives, and preventive measures, is discussed. Additionally, the challenges faced by nursing staff in promoting oral health and potential solutions are addressed. The review highlights the importance of interdisciplinary collaboration between nursing staff, oral health professionals, and other healthcare providers to optimize oral health outcomes in the general population. Future directions for research and practice in this area are also considered.