To study the quantitative structure-property relationship of molecules, the efficient tools are the topological indices. This is mainly due to the fact that these families of networks have topologies that reflect the communication pattern of a wide variety of natural problems. Mesh/torus-like low-dimensional networks have recently received a lot of attention for their better scalability to larger networks, as opposed to more complex networks such as hypercubes. There is a lot of relevant work on interdependent networks which can be reviewed. In particular, the failure of cooperation on dependent networks has been studied a lot recently. The topological indices of certain interconnection networks got the attention of many researchers in recent years. In this connection, we study the topological invariants associated with certain Sudoku networks.